cgenomics

How the closest relatives of eukaryotes grew a larger genome

Asgard archaea have emerged as key organisms to understand eukaryogenesis. Among their many fascinating features is their atypically large genomes. Here, we dive deep into Asgard genome evolution to understand the interplay of gene transfer and duplication in shaping eukaryotes’ closest relatives. Read the article

0
Read More

Multidimensional assessment of in-host fitness costs of echinocandin resistance in the opportunistic fungal pathogen Candida glabrata reveals the niche-specific requirement for FKS1 and FKS2 during infection and gut colonization.

Arastehfar A, Daneshnia F, Hovhannisyan H, Cabrera N, Jusuf S, Salehi M, Mansour MK, Gabaldón T, Shor E, Perlin DS. Multidimensional assessment of in-host fitness costs of echinocandin resistance in the opportunistic fungal pathogen Candida glabrata reveals the niche-specific requirement for FKS1 and FKS2 during infection and gut colonization. Antimicrob Agents Chemother. 2026 Mar 23:e0180125. doi: 10.1128/aac.01801-25. Epub ahead of print. PMID: 41870047.

0
Read More