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How the closest relatives of eukaryotes grew a larger genome
Asgard archaea have emerged as key organisms to understand eukaryogenesis. Among their many fascinating features is their atypically large genomes. Here, we dive deep into Asgard genome evolution to understand the interplay of gene transfer and duplication in shaping eukaryotes’ closest relatives. Read the article...
Phylogenomics of Asgard archaea reveals a unique blend of prokaryotic-like horizontal transfer and eukaryotic-like gene duplication.
Manzano-Morales S, Gabaldón T. Phylogenomics of Asgard archaea reveals a unique blend of prokaryotic-like horizontal transfer and eukaryotic-like gene duplication. Nat Commun. 2026 Apr 10. doi: 10.1038/s41467-026-71534-5. Epub ahead of print. PMID: 41963319...
Multidimensional assessment of in-host fitness costs of echinocandin resistance in the opportunistic fungal pathogen Candida glabrata reveals the niche-specific requirement for FKS1 and FKS2 during infection and gut colonization.
Arastehfar A, Daneshnia F, Hovhannisyan H, Cabrera N, Jusuf S, Salehi M, Mansour MK, Gabaldón T, Shor E, Perlin DS. Multidimensional assessment of in-host fitness costs of echinocandin resistance in the opportunistic fungal pathogen Candida glabrata reveals the niche-specific requirement for FKS1 and FKS2 during infection and gut colonization. Antimicrob Agents Chemother. 2026 Mar 23:e0180125. doi: 10.1128/aac.01801-25. Epub ahead of print. PMID: 41870047...
Stability of oral and fecal microbiome at room temperature: impact on diversity
Rius-Sansalvador B, Bars-Cortina D, Khannous-Lleiffe O, Garcia-Serrano A, Guinó E, Saus E, Gabaldón T, Moreno V, Obón-Santacana M. Stability of oral and fecal microbiome at room temperature: impact on diversity. Front Microbiomes. 2025 Apr 30;4:1334775. doi: 10.3389/frmbi.2025.1334775. PMID: 41852417; PMCID: PMC12993597...
Antifungal and anti-virulence activities of cinnamon, thyme, and clove essential oils against Candida species
Ahaik I, Nunez-Rodriguez JC, Abelló-Cros S, Yanes O, Bouhdid S, Gabaldón T. Antifungal and anti-virulence activities of cinnamon, thyme, and clove essential oils against Candida species. Front Pharmacol. 2026 Mar 2;17:1756267. doi: 10.3389/fphar.2026.1756267. PMID: 41847137; PMCID: PMC12989488...
