Group leader: Toni Gabaldón
Gabaldon’s group is jointly affiliated to the Biomedical Research Institute (IRB) and the Barcelona Supercomputing Centre (BSC), at Barcelona (Spain) . The main research interest of our group is to understand the complex relationships between genome sequences and phenotypes and how these two features evolve within and across species. We generally use large-scale phylogenetics and molecular evolution approaches that allow looking at the evolution of genomes from the perspective of all of their genes, and we apply these analyses to a variety of biological questions related the evolution and function of biological systems, ranging from individual molecules to entire biological communities.
News

Our Caixa Research project on evolutionary emergence of antifungal resistance is highlighted in this blog entry on fungi and their relevance for health
At the article they interviewd our Group leader, Toni Gabaldon as leader of a CaixaResearch project aimed at discovering new drugs against candidiasis.One of the challenges for antifungal treatments is the emergence of resistant strains.The research group seeks to decipher which mutations favor the resistance of the ‘Candida’ fungus. Read the article at Caixa Research…

Jesse Willis, winner of the Excellence in Doctoral Thesis in Bioinformatics Awards by Bioinformatics in Barcelona.
We are happy to share that our past member, Jesse Willis has won the award with the thesis Oral Microbiome: Composition, Interactions and Shaping Factors (2021), directed by Toni Gabaldón and performed in our group. . This thesis provides for the first time a global view of the oral microbiome of the Spanish population, revealing…
The MultiSeq project receives funding from the ERC to optimise sequencing and explore market potential
• The laboratory led by Dr. Toni Gabaldón at IRB Barcelona and the BSC is exploring an innovative solution that minimises the time and cost of sequencing.• The MultiSeq project has received an ERC Proof of Concept grant endowed with €150,000, for a period of 18 months.Read the article at IRB website